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Identification of CNV-miRNAs as genetic drivers and risk factors for congenital anomalies of the kidney and urinary tract (CAKUT)

Principal Investigator Ivan Jovanović, PhD, Assistant Research Professor

Project granted by the Science Fund of the Republic of Serbia,
Program for excellent projects of young researchers (PROMIS)

News


miFaDriCa project has published the results which expand the understanding of CNV-affected miRNAs potential to participate in CAKUT as genetic drivers thus representing a crucial implication for the development of novel therapeutic approaches. 

Mitrovic K, Zivotic I, Kolic I, Djordjevic A, Zakula J, Filipovic Trickovic J, Zivkovic M, Stankovic A, Jovanovic I. Identification and functional interpretation of miRNAs affected by rare CNVs in CAKUT. Sci Rep. 2022 Oct 22;12(1):17746. doi: 10.1038/s41598-022-22749-1.
Link of the publication:
https://www.nature.com/articles/s41598-022-22749-1


The results of the miFaDriCa Project have been reported on the  European Society of Human Genetics – ESHG Conference with a  full fellowship grant
11th to 14th June 2022, Vienna, Austria

I. Kolic, K. Mitrovic, I. Zivotic, A. Djordjevic, J. Filipovic Trickovic, M. Zivkovic, A. Stankovic, I. Jovanovic. Assessing the burden of rare CNVs on miRNA genes in CAKUT. ESHG 2022, Hybrid Conference Vienna, Austria, June 11–14, 2022. P12.027.A


The First results of the miFaDriCa Project have been reported on the  European Society of Human Genetics – ESHG Conference with full fellowship grants for both presenters
28th to 31st August 2021


Mitrovic, K., Kolic, I., Zivotic, I., Filipovic Trickovic, J., Djordjevic, A., Zivkovic, M., Stankovic, A., Jovanovic, I. Are miR-548 family members potential genetic drivers of CAKUT. ESHG 2021, Virtual Conference, August 28.-31., 2021.P11.024.B/B 
Link: https://www.abstractsonline.com/pp8/#!/10372/presentation/1047
Presentation download 

Zivotic, I., Kolic, I., Mitrovic, K., Filipovic Trickovic, J., Djordjevic, A., Zivkovic, M., Stankovic, A., Jovanovic. I. miRNA-free rare pathogenic CNVs could drive toward variable CAKUT phenotypes. ESHG 2021, Virtual Conference, August 28.-31., 2021. P11.023.A/A

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